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The physician author at Bonza Health explicitly states she would not currently recommend TB-500 given preclinical signals of thymosin beta-4 upregulation in pancreatic, colorectal, gastric, and non-small cell lung cancers

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PLoS Pathog 8:e1002620 Lim YS, Shin KS, Oh SH, Kang SM, Won SJ, Hwang SB (2012) Nonstructural 5A protein of hepatitis C virus regulates heat shock protein 72 for its own propagation